CALCRL and thoracic aortic aneurysm: According to that study [25], a molecular signature of eight genes (CDH5; Calcitonin Receptor-Like Receptor-Kinase Insert Domain Receptor–KDR, CALCRL; Activin A Receptor-Like Type 1-ACVRL1, Purinergic Receptor P2X 4-P2RX4, Protein Tyrosine Phosphatase Receptor Type J-PTPRJ, Tryptophanyl-TRNA Synthetase 1–WARS, and Junction Plakoglobin-JUP) were identified as potential biomarkers associated with thoracic aortic aneurysms.