RIPK1 and depressive symptom measurement: Finally, Safari-Arababadi et al. evaluated the relationship between depression and anxiety with the expression of some inflammatory transcription factors, which are the receptor-interacting protein 1 (RIP1) and the IFN-β promoter stimulator-1 (IPS-1) in the peripheral blood mononuclear cells of CHB patients, known as the critical molecules against HBV [79].