Similarly, among the secondary metabolites present in chia that may be involved in its health-promoting activities, we mention ellagic acid due to its potent antioxidative and anti-inflammatory activities, especially in complications deriving from DM by the activation of multiple pathways such as radical production, the GPX/GSH system, NO/iNOS generation, AGE/ALE, JNK/ERK, and GLUT4. Here, NOS2 is linked to diabetes mellitus.