EGFR and cancer: Protein pathway analysis was performed using STRING database [59], and common proteins were related to the following: viral protein interaction with cytokine and cytokine receptor; microRNAs in cancer; cytokine–cytokine receptor interaction; and phospholipase D, Rap1, PI3K-Akt, JAK-STAT, chemokine, calcium, Ras, and MAPK signaling pathways; EGFR tyrosine kinase inhibitor resistance; and other cancer pathways (Figure 3C).