The median Ang1 levels in COVID-19 patients (severe and non-severe) was mildly decreased with a median of 18,265.3 pg/mL (IQR: 12,533–25,660), while in healthy controls, the median Ang1 levels was 29,441.2 pg/mL (IQR: 25,953.5–32,703.7) (Mann–Whitney U P = 0.075). Here, ANGPT1 is linked to COVID-19.