In the light of the observation that vasculitis and vasculopathy pose a major threat during COVID-19 infections, we set out to evaluate the patients’ plasma levels of some of the key secreted signaling molecules involved in angiogenesis, including angiopoietin-1 (Ang1), angiopoietin-2 (Ang2) [1], as well as the cytokine interleukin-6 (IL-6) [2] that causes vascular repercussions. This evidence concerns the gene ANGPT2 and vascular disorder.