Male gender (1.917, 95% CI [1.007, 3.646], p = 0.047), older age (1.034, 95% CI [1.005, 1.063], p = 0.019), higher AFP levels (1.004, 95% CI [1.000, 1.007], p = 0.024), and higher AST levels (1.009, 95% CI [1.003, 1.015], p = 0.006) were associated with a higher probability to have a diagnosis of HCC at baseline in the CHB group. Here, AFP is linked to hepatocellular carcinoma.