MALAT1 and breast carcinoma: For example, by knocking out the MALAT1 (metastasis associated lung adenocarcinoma transcript 1) gene with the use of clustered regularly interspaced short palindromic repeats (CRISPR) editing in the MDA-MB-361 breast cancer cell line, decreased proliferation and increased apoptosis has been observed, a phenomenon which can be further studied in vivo in a clinical setting for breast cancer patients [67].