A significant decrease in the levels of TNF-α present in the sera of BALB/c mice implanted with the F3II tumor was observed when treated with 6.25 (p < 0.01); 12.5 (p < 0.01) and 25 mg/kg (p < 0.05) of H. junceus scorpion venom (Figure 4A). Here, TNF is linked to neoplasm.