PLN and familial dilated cardiomyopathy: In cases of DCM associated with pathogenic or likely pathogenic genetic variants in specific genes, such as lamin A/C (LMNA), filamin C (FLNC), transmembrane protein 43 (TMEM 43), phospholamban (PLN), desmoplakin (DSP), and RNA binding motif protein 20 (RBM20), the arrhythmic risk is higher [13,17,18,19,20,21].