Multiple studies, including those by our team, have shown the power of 1HMRS to predict (i) the ki-67 index range of value, (ii) the increase of tumor vasculature [18], (iii) the detection of 2-HG, the oncometabolite generated by the IDH 1/2 mutation, for its successful identification [19] and tumor heterogeneity assessment [20]. This evidence concerns the gene IDH1 and neoplasm.