When NSE was measured 72 h after cardiac arrest, we also observed statistically significant disparities in NSE values between survivors and decompensated patients, both in terms of all the studies analyzed (34.08 ± 36.56 vs. 122.03 ± 67.15 μg/L; SMD = −2.98; 95% CI: −3.95 to −2.01; p < 0.001) and in the sub-analysis of OHCA patients (35.9 ± 37.5 vs. 129.1 ± 66.7; SMD = −3.03; 95% CI: −4.22 to −1.83; p < 0.001). The gene discussed is ENO2; the disease is cardiac arrest.