Germline predisposition to myeloid neoplasms has been reported in relation to germline alterations in CEBPA, DDX41, TP53, RUNX1, ANKRD26, ETV6, GATA2, and SAMD9/SAMD9L as well as alterations in genes associated with bone marrow failure syndromes (Fanconi anemia, dyskeratosis congenita and related telomere biology disorders, Diamond–Blackfan anemia, and Shwachman–Diamond syndrome) [9,10,11,12]. The gene discussed is GATA2; the disease is Fanconi anemia.