SERPINE1 and gastric cancer: As shown in Figure 4A, we found that the most significantly hallmark pathways, including MYC_TARGETS_V1, EPITHELIAL_MESENCHYMAL_TRANSITION, OXIDATIVE_PHOSPHORYLATION, and TNFA_SIGNALING_VIA_NFKB, were upregulated in gastric cancer samples with high SERPINE1 expression.