Together with anti-cardiolipin (aCL) and anti-β2-glycoprotein-I (anti-β2GPI), lupus anticoagulant (LA) belongs to a group of three so-called criterion antiphospholipid antibodies (aPL), the positive finding of which, according to the International Society on Thrombosis and Haemostasis (ISTH), is one of the defined laboratory criteria for the diagnosis of antiphospholipid syndrome (APS) [1,2,3,4,5,6]. This evidence concerns the gene FASLG and autoimmune polyendocrinopathy.