GPT and liver failure: As expected, the body weight, liver weight, and spleen weight of the ALI rats were significantly lower than those of the control rats, and the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBL), and serum ammonia of the ALI rats were significantly higher than those of the control rats, indicating that the TAA-induced liver failure model was successfully developed.