Moreover, ERU was found to inhibit the tumor growth in human triple-negative breast cancer cells [52] as well as in a breast cancer cell xenograft mouse model; interestingly, in this case a regulation of mitochondrial fission/fusion emerges, in particular with the translocation of cofilin and Drp1 and consequent cell apoptosis [53]. The gene discussed is CFL1; the disease is triple-negative breast carcinoma.