Furthermore, both the map-based OGM SV algorithm and the coverage-based CNV algorithm detected an 18.8 Mbp heterozygous deletion on chr20 in a myeloproliferative neoplasms (MPN) genome (BNGOHM-0000176), impacting multiple genes associated with myeloid neoplasms, such as L3MBTL1 and SGK2 (Figure 3b). The gene discussed is L3MBTL1; the disease is myeloproliferative disorder.