IL2 and neoplasm: With regards to the latter, it has been previously demonstrated that IL-2 and Hsp70-primed CD3−/CD56+ NK cells, which exhibit an increased cell surface density of the C-type lectin receptor complex CD94/NKG2A/C and the activatory receptor CD69, can recognize and kill tumor cells expressing mHsp70 via granzyme B-mediated apoptosis [33].