MSH2 and neoplasm: Four criteria with clinical significance were analyzed—the whole blood MSH2 concentration, reflecting the mass transfer from the tumor mass to blood, the ratio between whole blood MSH2 concentration and urine MSH2 concentration, reflecting the elimination of MSH2 via the kidneys, the ratio between whole blood MSH2 concentration and saliva MSH2 concentration, reflecting the elimination of MSH2 via the salivary glands, and the sum S = 2 × [MSH2]urine + [MSH2]saliva, reflecting the total elimination via both ways under the assumption that urine daily volume is twice the saliva daily volume.