MSH2 and adenocarcinoma: In tissue samples, a vegetant gross aspect of adenocarcinomas was slightly related to a lower MSH2 level as 65.4% of the tumors that have a vegetant compound (vegetant or ulcerated and vegetant tumors) are associated with MSH2 levels < 150 pg/mL compared with only 43.3% for the ones that do not have a vegetant compound.