MGMT and glioblastoma: As per our observation of molecular biological status, FNDC3B expression was universally increased in Grade 4 where glioblastoma is included, regardless of whether the groups were MGMT methylated (3.0-fold, p < 0.0001) or unmethylated (3.2-fold, p < 0.0001), IDH-mutated (3.6-fold, p < 0.0001) or IDH-wild type (4.2-fold, p < 0.0001).