In sum, the present study confirms that high AMH levels may impair the ovarian response in women with PCOS undergoing IVF, and could be of clinical utility to predict treatment outcomes, as recently shown by a systematic review and meta-analysis which suggested that AMH could be useful for counseling women with PCOS, who wish to undergo fertility treatments, on the expected IVF outcomes, although large-scale, high-quality cohort studies are still needed to confirm these findings [56]. The gene discussed is AMH; the disease is polycystic ovary syndrome.