An immunophenotypic analysis from isolated prostatectomy specimens demonstrated an increase of CD11b+CD68+CD14+HLA-DRhigh monocytes and CD11b+CD68−CD16+HLA-DRlow monocytes among the CD11b+ myeloid cells, a high fraction of CD8+ T cells within total CD45+ immune cells in PCa tissues and an increase of CD4+ forkhead box subfamily 3+ (FOXP3+) in high-grade PCa compared to low-grade PCa [103]. Here, CD4 is linked to posterior cortical atrophy.