Antiphospholipid antibody syndrome (APS) is an autoimmune disorder characterized by thrombosis (arterial and/or venous) and/or pregnancy morbidity in association with circulating antiphospholipid antibodies (aPL), among which the main are the anti-β2 glycoprotein 1 antibodies (anti-β2-GPI antibodies) [1,2]. The gene discussed is APOH; the disease is autoimmune disease.