Second, with regard to thrombosis of other organs, COVID-19 severity and aPLA, two patients with COVID-19 pneumonia developed arterial thrombosis during hospitalization—one developed cerebral artery thrombosis and was positive for aCL IgG, anti-β2GPI IgM, and aPS/PT IgM on admission. The gene discussed is CD40LG; the disease is Arterial thrombosis.