Nevertheless, in a subgroup analysis of people with type 2 diabetes, both patients with MACS and Cushing’s syndrome required insulin treatment more frequently than patients with NFAI (aPRs, 1.89 (CI, 1.01 to 3.52) and 3.06 (CI, 1.60 to 5.85), respectively). This evidence concerns the gene INS and type 2 diabetes mellitus.