Figure 3 shows there was a positive significant (p < 0.05) correlation between the ESR1 gene expression level and EFNA1 expression in BRCA-LumA cancer patients as well as the ROBO1 expression level in BRCA-Basal patients, but a negative significant (p < 0.05) correlation between the ESR1 and KLK6 gene expression levels in BRCA-LumA and BRCA-LumB patients, as well as between the KLK6, LIMK2, and ROBO1 expression levels in all BRCA patients. Here, ESR1 is linked to cancer.