Additionally, patients with severe APTB exhibited significantly higher levels of IL-6 (8.16 pg/mL; p < 0.05), IFN-γ (10.15 pg/mL; p < 0.05), IL-33 (118.4 pg/mL; p < 0.05), and CHIT1 (23.96 ng/mL; p < 0.05) compared to those with mild TB (IL-6: 3 pg/mL; IFN-γ: 4.8 pg/mL; IL-33: 56.89 pg/mL; CHIT1: 11.04 ng/mL) at T2 (Figure 2A,B). Here, IFNG is linked to tuberculosis.