Studies have shown that biomarkers including NEK7 [206], CAV1 [210], TRIB3 [182], STAT1 [812], TP53 [813], and NFKB1 [814] are closely related to the development of diabetes mellitus.Some papers reported that NEK7 [337], BMI1 [297], CAV1 [341], TRIB3 [304], TTN (titin) [300],hsa-mir-19b-3p [815], hsa-mir-941 [816], NFYA (nuclear transcription factor Y subunit alpha) [817], STAT1 [818], MEF2A [819], TP53 [820], and NFKB1 [821] have been revealed to be associated with heart failure. The gene discussed is TRIB3; the disease is heart failure.