Some of the pathways that are enriched with the up-regulated genes are associated with cancer, such as epithelial to mesenchymal transition in colorectal cancer (FDR = 6%), PI3K-AKT signaling pathway (FDR = 2%) and focal adhesion-PI3K-AKT-mTOR (FDR = 8%). This evidence concerns the gene PIK3CA and colorectal cancer.