As shown in Figure 1, compared with the CTR group, coccidia and C. perfringens infection significantly reduced mRNA levels of leucine-rich repeat containing G protein-coupled receptor 5 (Lgr5), zinc and ring finger 3 (Znrf3), caudal-type homeobox 1 (cdxA), and cdxB in jejunum on day 13, as well as cdxB gene expression in jejunum on day 19 (p < 0.05). The gene discussed is LGR5; the disease is infection due to clostridium perfringens.