These partners included cell division cycle 42 (CDC42), growth factor receptor-bound protein 2 (GRB2), glycogen synthase kinase 3 beta (GSK3B), epidermal growth factor receptor (EGFR), breast cancer anti-estrogen resistance 1 (BCAR1), disheveled, Dsh homolog 1 (DVL1), ubiquitin C (UBC), sex hormone-binding globulin (SHBG), androgen receptor (AR), and iodide. The gene discussed is SHBG; the disease is breast carcinoma.