Most notably, PHI-1 upregulation has been consistently observed across various malignancies, including ovarian clear cell carcinoma, chronic lymphocytic leukemia, prostate cancer, glioblastoma, triple-negative breast cancer, and uterine corpus endometrial carcinoma [32,33,34,37,38,55]. The gene discussed is PPP1R14B; the disease is triple-negative breast carcinoma.