In addition, a significant association was found between HS and CRP in children with newly diagnosed, previously untreated JIA [(TP), (r = 0.7221; p = 0.0000)], the patients with remission of JIA resulting from treatment with MTX, SSA and EC [(TR), (r = 0.7104; p = 0.0001)], and the patients with aggressive disease before ETA treatment [(T0), (r = 0.8048; p = 0.00000)]. Here, CRP is linked to juvenile idiopathic arthritis.