POR and congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency: Homozygous or compound heterozygous mutations in the human POR gene (MIM: *124015) give rise to a diverse spectrum of clinical manifestations known as POR deficiency (PORD; MIM: #613571) in an autosomal recessive inheritance [7,10,11,12,13,14,15,16,17,18].