Among others, the pan-HDACi vorinostat (SAHA) was found to reduce the incidence and severity of the murine experimental autoimmune encephalomyelitis (EAE) model for MS as well as induce peroxisomal activity in ABCD1-deficient fibroblasts and astrocytes [39,40]. The gene discussed is ABCD1; the disease is myeloid sarcoma.