CD8A and acute lymphoblastic leukemia: To determine whether FMD + VC may promote immune-dependent killing of B-ALL cells, we treated ALL mice with a single FMD cycle (n = 24 mice) and collected bone marrow, spleen and blood for flow cytometry analyses of the following T cell markers: CD3+CD4+, CD3+CD8+, CD4+CD25+, CD4+PD-1+, CD8+CD25+ and CD8+PD-1+ (Figure 6a,b).