ABL1 and acute lymphoblastic leukemia: To investigate whether autophagy inhibition may enhance or mediate the effects of fasting/FMD and VC against ALL progression in vivo, a syngeneic mouse model of BCR-ABL was treated with the autophagy inhibitor chloroquine in combination with an ad lib diet or FMD ± VC (n = 8/groups) (Figure 4a).