However, while immunohistochemistry is not helpful for the distinction between thecoma and luteinized adult granulosa cell tumor or between juvenile and adult granulosa cell tumor, the presence of FOXL2 variant allows the diagnosis of adult granulosa cell tumor, while the DICER1 variant favors that of luteinized juvenile granulosa cell tumors or SLCTS [8,19,46]. This evidence concerns the gene DICER1 and granulosa cell tumor.