In another study, a similar 19-day protocol of voluntary wheel running resulted in the hypertrophy of type II muscle fibres in colon-cancer-bearing mice and led to the normalisation of paired box 7 (Pax7) protein expression, which dysregulation is related to the malfunction of muscle satellite cells (please see next paragraph) [121]. The gene discussed is PAX7; the disease is malignant colon neoplasm.