To investigate the role of CILP2 in pancreatic cancer progression in vivo, we developed orthotopic and liver metastasis pancreatic cancer models using stably transfected cell lines (PANC-1-Vector, PANC-1-CILP2, BxPC-3-shCtrl, and BxPC-3-shCILP2). Here, CILP2 is linked to pancreatic neoplasm.