IFNG and neoplasm: On the other hand, treatment of PDX mice with both p402 mAb and p40 mAb led to a significant decrease in CA19-9 (Figure 8D,F) and a marked increase in IFNγ (Figure 8D,E) in tumor tissues, indicating an improvement in disease prognosis in comparison to either untreated control or IgG-treated PDX mice.