Indeed, the increased presence of NKG2DL among in vitro GBM cell lines treated with Temozolomide (TMZ) was linked with increased γδ T cell lysis of the GBM cells when in co-culture, indicating that the expression of NKG2D in γδ T cells contributes to their ability to recognize and lyse tumor cells [24]. Here, KLRK1 is linked to glioblastoma.