CD4 and neoplasm: The median density of CD4+ TIIs in the tumor area of GC tissue was 30.8 (range, 1–326) cells/HPF (high-power field); that of CD8+ TIIs was 49.6 (2–523) cells/HPF; that of CD86+ TIIs was 0.4 (1–43) cells/HPF; that of CD163+ TIIs was 19.4 (1–184) cells/HPF; and that of CD25+ TIIs was 0 (0–11) cells/HPF (Supplementary Table S2).