MYC and Burkitt lymphoma: Thus, Plasmodium falciparum infection is associated with EBV-associated endemic Burkitt’s lymphoma development in Sub-Saharan Africa and Papua New Guinea, weakening EBV-specific immune control and inducing elevated viremia by lytic cycle reactivation as well as stimulating expression of the mutagenesis machinery that is required for the c-myc translocation that is characteristic of Burkitt’s lymphoma.