For cases analyzed with WGS, the translocation partner of TERT was identified and indicated multiple loci with established functions in NB tumorigenesis, such as MYCN (2p), HAND2 (4q), GATA3 (10p), CCND1 (11q), RBFOX1 (16p), and DLG2, a gene with a role in neural differentiation and a tumor suppressor gene candidate in 11q-deleted NB [40,41] (Figure 1A). This evidence concerns the gene HAND2 and neuroblastoma.