For example, Merlin (Neurofibromain 2), a tumor suppressor [10]; G-protein coupled receptor [11]; miRNAs [12]; and adherens, tight junctions, and signaling pathways (MAPK, Notch, and Wnt/β-catenin) [13] inhibit the activity of YAP/TAZ by promoting phosphorylation by activating the kinases. The gene discussed is NF2; the disease is neoplasm.