PBRM1 and peritoneal mesothelioma: Furthermore, in the peritoneal mesothelioma cohort in the previously cited study [21], the most common alterations detected in peritoneal mesothelioma were inactivating mutations in BAP1 (47.9%), NF2 (26.5%), CDKN2A (25.9%), CDKN2B (19.5%) and PBRM1 (15.8%).