Teussing et al. have demonstrated in a small clinical study on five Stargardt’s disease patients with identified disease-related mutations in ABCA4 gene that protecting one eye from light by wearing for at least 11 months a black contact lens during waking hours results in a smaller percentage of hypofluorescent pixels in the fundus fluorescence image, corresponding to focal losses of the RPE, in comparison with the unprotected fellow eye [268]. This evidence concerns the gene ABCA4 and Stargardt disease.