ACHE and Cognitive impairment: Piceatannol (a resveratrol analog, also called 3′-hydroxyresveratol) was reported to exhibit in vitro DPPH-radical-scavenging activity, anti-AChE activities, inhibitions against Aβ peptide (1-42) aggregations, and neuroprotective activities against Aβ peptide (25-35)-induced cell death in SH-SY5Y cell models, resulting in a reduction in cognitive impairment in scopolamine-induced amnesiac ICR mice [23].