Resveratrol could suppress leukemia cell proliferation and induce apoptosis due to increased expression of PTEN (the phosphatase and tensin homolog deleted on chromosome ten) and the inhibition of the activity of PI3K/AKT signaling pathway, resulting in decreased tumor cell proliferation, division, activated apoptosis, reduced angiogenesis, and formation of metastases [89]. Here, AKT1 is linked to neoplasm.