Severe delirium was associated with rising trends in the serum levels of inflammatory markers, e.g., TNF-Alpha (p = 0.084 at 24 h and p = 0.087 at 72 h), Interleukin-8 (p = 0.032 at 24 h and p = 0.082 at 72 h), and Lipocalin-2 (p = 0.004 at 24 h and p = 0.078 at 72 h) (Figure 4) in all studied subjects. The gene discussed is CXCL8; the disease is delirium.